Yes I think it's entirely possible. Again, there are threads about all the games the Sabres have lost due to injury and yet they're still within reach. They're getting healthier and their records shows it.
Even more in our favor is the Sabres haven't played the last two nights and they lost.... one point in the standings. The teams ahead of them are not tearing it up. There precisely 2 teams in the Eastern Conference on winning streaks (i.e., more than one win in a row): Tampa with a 4 game streak, and your Buffalo Sabres with a modest 2 game streak.
Sure, the Sabres have struggled this year. But so has just about EVERY team in the East. A quarter of the way through the season, there's only a 9 point difference between first and last in the Eastern Conference. Compare that to the Western Conference where there's a 21 point gap between first and last. The Wildcard, Division, and Conference are all up in the air right now.
Whatever team can string a few wins together will be in the driver's seat. So far, none of the teams in the East have done that really. The first two weeks of December will tell us if the Sabres have a chance: 6 out of 7 games on the road. If they can win on the road in December, they'll make the playoffs.